Mol. Mass:


Other Common Names

 Metocin, 4-hydroxy-N-methyl-N-ethyltryptamine, methylcybin


 Off white, almost peach colored grainy powder.



4-HO-MET is a lesser known psychedelic tryptamine that first received attention after its synth and properties were published in the book Tryptamines I’ve known and Loved by Ann & Alex Shulgin(link below). Structurally it is the 4-hydroxyl version of MET. Interestingly enough, due to 4-HO-METs effects and pharmacological properties, it is also labeled as a functional analog of psilocin* or 4-HO-DMT. Besides the wealth of information provided in TiHKAL, very little scientific data has been published as to its pharmacological characteristics. The effects of 4-HO-MET mirror those of Psilocin in just about every way. Some of the more notable effects include the distortion of color, sound, and forms as well as close/open eye visuals, euphoria, and laughter. The duration is said to range from 4 – 6 hours, with the intensity of the experience following a wavelike pattern.

*Psilocin- A hallucinogenic alkaloid found in most species of psychedelic mushrooms.



Dosage is documented as extremely tentative so it should never be weighed with anything other than a miligram scale(.000). A staggering amount of user reports proclaiming the listed threshold was overly intense while others say that the heaviest dose listed barely produced any effect. As with all research chemicals, 4-HO-MET should be treated with great care and not taken lightly. Remember, everyone reacts differently to different things. In TiHKAL, 10-20mg was listed as a light/common dose. Users report threshold being around 5mg and a heavy dose at the 25+mg mark. This is debated though, with others noting that it took a whopping 30mg for threshold effects.


Legal Status:

No legislation specifically mentions 4-HO-MET as a scheduled substance. This by no means indicates it is completely legal, especially if you are caught selling it under the alias of a controlled substance or even mention the intention of consumption. 4-HO-MET could be tried under the analog act due to its similarity psilocin and psilocybin.